Ventricular Remodeling Induced by Tissue Vitamin A Deficiency in Rats
نویسندگان
چکیده
منابع مشابه
Atrophic Cardiac Remodeling Induced by Taurine Deficiency in Wistar Rats
INTRODUCTION Micronutrient deficiency is observed in heart failure patients. Taurine, for example, represents 50% of total free amino acids in the heart, and in vivo studies have linked taurine deficiency with cardiomyopathy. METHODS Thirty-four male Wistar rats (body weight = 100 g) were weighed and randomly assigned to one of two groups: Control (C) or taurine-deficient (T (-)). Beta-alanin...
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Retinoic acid (RA) plays a role in regulating cardiac geometry and function throughout life. The aim of this study was to analyze the cardiac effects of RA in adult rats. Wistar rats were randomly allocated to a control group (n = 18) receiving standard rat chow and a group treated with RA (n = 14) receiving standard rat chow supplemented with RA for 90 days. All animals were evaluated by echoc...
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BACKGROUND It is not fully clarified how diabetes mellitus (DM)-induced cardiac dysfunction is associated with histopathological changes of the heart in a long lasting period of DM. METHODS AND RESULTS Eighteen weeks after a streptozotocin injection was given to Wistar - Kyoto rats (D rats), echocardiography and hemodynamic studies including the dobutamine infusion test were performed. After ...
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متن کاملTissue vitamin A insufficiency results in adverse ventricular remodeling after experimental myocardial infarction.
BACKGROUND/AIMS The role of tissue vitamin-A insufficiency on post-infarction ventricular remodeling is unknown. We tested the hypothesis that cardiac vitamin A insufficiency on post-infarction is associated with adverse myocardial remodeling. METHODS After infarction, rats were allocated into two groups: C (controls, n=25); VA (dietary vitamin A restriction, n= 26). After 3 months, the anima...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2010
ISSN: 1421-9778,1015-8987
DOI: 10.1159/000320563